How to obtain consistent results in breath analysis with SUPER SESI and EXHALION?

To ensure the reliability of the breath test data, this study includes a systematic evaluation of the sources of variability and strategies to minimize their impact. 

Breath is very dynamic:

• The exhalation profile is very variable, with upper airways species coming first, and the alveolar fraction coming at the end. To solve this, EXHALION captures the CO2 profile and differentiates lung fractions.

• Breath can change from one exhalation to the next. EXHALION guides the exhalation maneuver to induce a steady-state.

The instrument-SoP variability of this study is below person-to-person differences. This allows researchers to capture biological differences. 

Click here to find this article: https://www.fossiliontech.com/sesi-publications/standardization-procedures-for-real-time-breath-analysis-by-secondary-electrospray-ionization-high-resolution-mass-spectrometry