Secondary Electrospray Ionization (SESI) of Ambient Vapors for Explosive Detection at Concentrations Below Parts Per Trillion
P. M-L Sinues, J. Rus, G. F. de la Mora, M. Hernández, and J. F. de la Mora
We determine the sensitivity of several commercial atmospheric pressure ionization mass spectrometers towards ambient vapors, ionized by contact with an electrospray of acidified or ammoniated solvent, a technique often referred to as secondary electrospray ionization (SESI).
Neutral desorption sampling of biological surfaces for rapid chemical characterization by extractive electrospray ionization mass spectrometry
H. Chen, R. Zenobi
Extractive electrospray ionization mass spectrometry (EESI-MS) allows the real-time, direct analysis of complex gaseous and liquid samples without any sample pretreatment under ambient conditions. By using a neutral desorption (ND) sampling gas beam to gently impact a surface, the analyte present on a surface can be efficiently sampled and then transported …
Direct Analysis of Fatty Acid Vapors in Breath by Electrospray Ionization and Atmospheric Pressure Ionization-Mass Spectrometry
P. M-L Sinues, J. F. de la Mora
Real time analysis of human breath is achieved in an atmospheric pressure ionization mass spectrometer (API-MS) by negatively charging exhaled vapors via contact with an electrospray cloud. The spectrum observed is dominated by a wide range of deprotonated fatty acids, including saturated chains up to C14. Above C14, the background from cutaneous sources becomes dominant.
Real-time, on-line monitoring of organic chemical reactions using extractive electrospray ionization tandem mass spectrometry
L. Zhu, G. Gamez, H. W. Chen, H. X. Huang, K. Chingin and Renato Zenobi
Extractive electrospray ionization mass spectrometry (EESI-MS) for real-time monitoring of organic chemical reactions was demonstrated for a well-established pharmaceutical process reaction and a widely used acetylation reaction in the presence of a nucleophilic catalyst, 4-dimethylaminopyridine (4-DMAP) …
Rapid classification of perfumes by extractive electrospray ionization mass spectrometry (EESI-MS)
L. Zhu, G. Gamez, H. W. Chen, H. X. Huang, K. Chingin and Renato Zenobi
Extractive electrospray ionization mass spectrometry (EESI-MS) for real-time monitoring of organic chemical reactions was demonstrated for a well-established pharmaceutical process reaction and a widely used acetylation reaction in the presence of a nucleophilic catalyst, 4-dimethylaminopyridine (4-DMAP) …