Comprehensive Real-Time Analysis of the Yeast Volatilome
A. Tejero-Rioseras, D. Garcia-Gomez, B. E. Ebert, L. M. Blank, A. J. Ibanez and P. M-L Sinues
While yeast is one of the most studied organisms, its intricate biology remains to be fully mapped and understood. This is especially the case when it comes to capture rapid, in vivo fluctuations of metabolite levels. According to the authors, the results suggest that a large number of metabolites produced by yeast from glucose neither are reported in the literature nor are their biochemical origins deciphered.
Fingerprinting Breast Cancer vs. Normal Mammary Cells by Mass Spectrometric Analysis of Volatiles
Jingjing He, P. M-L Sinues, M. Hollmén, Xue Li, M. Detmar & R. Zenobi
There is increasing interest in the development of noninvasive diagnostic methods for early cancer detection, to improve the survival rate and quality of life of cancer patients. Identification of volatile metabolic compounds may provide an approach for noninvasive early diagnosis of malignant diseases.
Rapid identification of bacteria in blood cultures by mass-spectrometric analysis of volatiles
C. Ballabio, S. Cristoni, G. Puccio, M. Kohler, M. R. Sala, P. Brambilla, P. M-L Sinues
Blood cultures are routine tests to determine whether micro-organisms have entered the patient’s bloodstream. Automated systems, based on the detection of CO2 increase in the culture media, have considerably improved the screening efficiency for the detection of bacteria. However, further identification of bacteria still requires time consuming culturing procedures.