Real-time, in vivo monitoring and pharmacokinetics of valproic acid via a novel biomarker in exhaled breath
Gerardo Gamez, Liang Zhu, Andreas Disko, Huanwen Chen, Vladimir Azov, Konstantin Chingin, Gunter Kramerb and Renato Zenobi
Valproic acid pharmacokinetics and ingestion in humans can be monitored through a novel biomarker in exhaled breath.
Secondary electrospray ionization-mass spectrometry: breath study on a control group
P. M-L Sinues, L. Zingaro, A. Finiguerra and S. Cristoni
A series of fatty acids among other compounds have recently been detected in breath in real time by secondary electrospray ionization mass spectrometry (SESI-MS). Our main aim in this work was to quantify their abundance in breath calibrating the system with standard vapors and extend the study to a control group for several days, both under fasting conditions and after sucrose intake.
Evaluation of extractive electrospray ionization and atmospheric pressure chemical ionization for the detection of narcotics in breath
C. Berchtold, L. Meier, R. Zenobi
Diagnosis by online breath analysis using mass spectrometry is challenging because of the low concentrations of pertinent compounds in breath. Here we investigate extractive electrospray ionization and atmospheric pressure chemical ionization for the detection of narcotics in breath.